Farmacotherapie van de posttraumatische stress stoornis. Een literatuuroverzicht van placebo gecontroleerd onderzoek

achtergrondPlacebogecontroleerd onderzoek naar de medicamenteuze behandel-mogelijkheden van de posttraumatische stressstoornis (PTSS) is pas in de laatste jaren duidelijk in kwaliteit en kwantiteit toegenomen. Omdat in de praktijk veelvuldig medicatie wordt voor-geschreven bij patiënten met PTSS, is kennis van de wetenschappelijke literatuur zeer relevant.
doelEen overzicht geven van de in de literatuur verschenen dubbelblinde placebogecontroleerde onderzoeken betreffende de farmacotherapie van de PTSS.

Special issue: 'Trauma and PTSD: Setting the research agenda'

Trauma and PTSD: setting the research agenda Miranda Olff, Cherie Armour, Chris Brewin, Marylene Cloitre, Julian D. Ford, Jane Herlihy, Ruth Lanius, Rita Rosner, Ulrike Schmidt, Stuart Turner

Re-experiencing traumatic events in PTSD: new avenues in research on intrusive memories and flashbacks Chris R. Brewin

The underlying dimensionality of PTSD in the diagnostic and statistical manual of mental disorders: where are we going? Cherie Armour

A plea for symptom-based research in psychiatry Ulrike Schmidt

Mobile mental health: a challenging research agenda

The field of mobile health (“m-Health”) is evolving rapidly and there is an explosive growth of psychological tools on the market. Exciting high-tech developments may identify symptoms, help individuals manage their own mental health, encourage help seeking, and provide both preventive and therapeutic interventions. This development has the potential to be an efficient cost-effective approach reducing waiting lists and serving a considerable portion of people globally (“g-Health”). However, few of the mobile applications (apps) have been rigorously evaluated.

Prolonged grief: setting the research agenda

Background: Prolonged grief disorder is proposed for the International Classification of Diseases (ICD-11), though it was rejected as a diagnosis for DSM-5.
Objective: This review outlines findings and defines important areas for future research viewed from a lifespan perspective.
Results: The development and psychometric evaluation of measures for the new diagnosis is paramount, specifically for children and adolescents. Treatments need to be adapted for specific subgroups and research findings have to be disseminated into various professional settings.

The Nonviolent Peaceforce in Sri Lanka: methods and impact (September 2003-January 2006)

Since 2003 the Nonviolent Peaceforce (NP) in Sri Lanka has aimed to increase the safety of civilians in Sri Lanka so that they can contribute to a lasting peace that includes a sense ofjustice.The NP has effectively assisted people to move to safer places, and supported people in interactions with authorities. The NP has also contributed to defusing ongoing violence and preventing further violence within specific situations.

The reintegration of teenage girls and young women

Women combatants are not a homogeneous group. The current approach of many Disarmament, Demobilization and Reintegration (DDR) programmes is inappropriate for girls between 14 and 25years of age. In order to provide reintegration assistance that has a significant long-term impact, it is essential first to understand why girls the join armed forces. Before DDR programme plans are finalized and programmes started, time and resources need to be investedfirstly to locate the girls and then begin the process of understanding their potentials, vulnerabilities, dreams and ambitions.

The ‘‘one size fits all’’ approach to trauma treatment: should we be satisfied?

There have been significant advances in the treatment of posttraumatic stress disorder in the last two decades. Further improvements in outcomes will be supported by recognition of the heterogeneity of symptoms in trauma populations and the development of treatments that promote the tailoring of interventions according to patient needs. Collaboration with patients regarding preferences about treatment structure, process, and outcomes is critical and will benefit the effectiveness and quality of treatments as well as the speed of their dissemination.

Complex PTSD: research directions for nosology/ assessment, treatment, and public health

Complex posttraumatic stress disorder (CPTSD) in children and adolescents extends beyond the core PTSD symptoms to dysregulation in three psychobiological domains: (1) emotion processing, (2) self-organization (including bodily integrity), and (3) relational functioning.

Trauma-related dissociation and altered states of consciousness: a call for clinical, treatment, and neuroscience research

The primary aim of this commentary is to describe trauma-related dissociation and altered states of consciousness in the context of a four-dimensional model that has recently been proposed (Frewen & Lanius, 2015). This model categorizes symptoms of trauma-related psychopathology into (1) those that occur within normal waking consciousness and (2) those that are dissociative and are associated with trauma-related altered states of consciousness (TRASC) along four dimensions: (1) time; (2) thought; (3) body; and (4) emotion.

Untested assumptions: psychological research and credibility assessment in legal decision-making

Background: Trauma survivors often have to negotiate legal systems such as refugee status determination or the criminal justice system. Methods & results: We outline and discuss the contribution which research on trauma and related psychological processes can make to two particular areas of law where complex and difficult legal decisions must be made: in claims for refugee and humanitarian protection, and in reporting and prosecuting sexual assault in the criminal justice system.

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