ARQ National Psychotrauma Centre


An epigenome-wide association study of posttraumatic stress disorder in US veterans implicates several new DNA methylation loci

Background: Previous studies using candidate gene and genome-wide approaches have identified epigenetic changes in DNA methylation (DNAm) associated with posttraumatic stress disorder (PTSD).

When a child dies : a systematic review of well-defined parent-focused bereavement interventions and their alignment with grief- and loss theories

Background: The availability of interventions for bereaved parents have increased. However, most are practice based. To enhance the implementation of bereavement care for parents, an overview of interventions which are replicable and evidence-based are needed. The aim of this review is to provide an overview of well-defined bereavement interventions, focused on the parents, and delivered by regular health care professionals.

The translation and validation of the dutch monash dog-owner relationship scale (Mdors).

The Monash Dog-Owner Relationship Scale (MDORS) is a questionnaire that is used to evaluate the perceived relationship between humans and their dog. This questionnaire was originally only formulated and validated in English, which limits its use among non-English speaking individuals. Although a translation could be made, the translation of questionnaires without additional validation often impairs the reliability of that questionnaire. Therefore, the aim of this study was to validate a translation of the MDORS that is suitable for use among native Dutch speakers.

How Thinking Hurts : Rumination, Worry, and Avoidance Processes in Adjustment to Bereavement

Repetitive negative thought plays an important role in the maintenance of mental health problems following bereavement. To date, researchers have primarily focused on rumination (i.e., repetitive thought about negative events and/or negative emotions) following loss, yet the interest in worry (i.e., repetitive thought about uncertain future events) is increasing. Both cognitive processes potentially lead to poorer adaptation to bereavement by contributing to loss-related avoidance and behavioral avoidance of activities.

Interactive Motion-Assisted Exposure Therapy for Veterans with Treatment-Resistant Posttraumatic Stress Disorder : A Randomized Controlled Trial

Background: Veterans with posttraumatic stress disorder (PTSD) tend to benefit less from evidence-based treatments than other PTSD populations. A novel virtual reality and motion-assisted exposure therapy, called 3MDR, provides treatment in an immersive, personalized and activating context.

Predictors of change during Narrative Exposure Therapy for displaced populations : A repeated measures design

Background: Displaced victims of interpersonal violence, such as refugees, asylum seekers, and victims of sexual exploitation, are growing in numbers, and are often suffering from a posttraumatic stress disorder (PTSD). At the same time these victims are known to benefit less from trauma-focused therapy, and to be less compliant to treatment. This paper describes the rationale and research protocol of an ongoing trial.

Prevalence of Potentially Traumatic Events, Other Life Events and Subsequent Reactions Indicative for Posttraumatic Stress Disorder in the Netherlands : A General Population Study Based on the Trauma Screening Questionnaire

Abstract: The 12-month and lifetime prevalence of posttraumatic stress disorder (PTSD) in different country populations has been assessed while using clinical interviews. Because this methodology is relatively time-consuming and resource-intensive, disaster health researchers adopted instruments, like the Trauma Screening Questionnaire (TSQ).

A Global Perspective on the Mental Health Response to Terrorism

Abstract. This chapter explores the association between terrorism, mental health and the capacity to provide evidence-based mass casualty intervention from a global perspective. The main message is there are vast differences in these three areas across countries and that, especially the last of the three, variation in service capacity and supportive conditions, influences the chances of implementing evidence-based guidelines.

Reviewing the Potential of Psychedelics for the Treatment of PTSD

There are few medications with demonstrated efficacy for the treatment of posttraumatic stressdisorder (PTSD). Treatment guidelines have unequivocally designated psychotherapy as a first line treatment for PTSD. Yet, even after psychotherapy, PTSD often remains a chronic illness, with high rates of psychiatric and medical comorbidity. Meanwhile, the search and development of drugs with new mechanisms of action has stalled. Therefore, there is an urgent need to explore not just novel compounds, but novel approaches for the treatment of PTSD.

Reciprocal relations between symptoms of complicated grief, depression, and anxiety following job loss : A cross-lagged analysis.

Objective: Involuntary job loss can lead to symptoms of complicated grief (CG), depression, and anxiety. Information about the temporal linkage between these symptoms is limited and may have implications for the treatment of those suffering from mental health complaints after dismissal. The aim of this study was to explore the possible reciprocal relationships between symptoms of CG, depression, and anxiety following involuntary job loss.