ARQ National Psychotrauma Centre

Engels

Rectal Sensitivity, but Not Drinking Capacity, is Associated With Stress Response in Healthy Volunteers and Patients With Functional Gastrointestinal Disorders

Introduction: Functional dyspepsia (FD) and irritable bowel syndrome (IBS) are two important functional gastrointestinal disorders. Factors that contribute to symptoms are psychosocial factors, traumatic events, stress response and sensitivity of the stomach and gut. Previous we have shown an association between these factors and stress reactivity. However, whether the acute physiological stress response affects gastrointestinal sensorimotor function remains unknown. In this study we explored this relation in healthy volunteers, FD and IBS.

PTSD in the military: special considerations for understanding prevalence, pathophysiology and treatment following deployment

Given the unique context of warzone engagement, which may include chronic threat, multiple and lengthy deployments, and loss, there is a need to understand whether and to what extent knowledge about PTSD derived from studies of civilian trauma exposure is generalizeable to the military. This special issue on PTSD in the military addresses a range of issues and debates related to mental health in military personnel and combat veterans.

Prevalence of mental health symptoms in Dutch military personnel returning from deployment to Afghanistan: A 2-year longitudinal analysis

Objective Recent studies in troops deployed to Iraq and Afghanistan have shown that combat exposure and exposure to deployment-related stressors increase the risk for the development of mental health symptoms. The aim of this study is to assess the prevalence of mental health symptoms in a cohort of Dutch military personnel prior to and at multiple time-points after deployment.

Pre-existing high glucocorticoid receptor number predicting development of posttraumatic stress symptoms after military deployment

Objective: The development of posttraumatic stress disorder (PTSD) is influenced by preexisting vulnerability factors. The authors aimed at identifying a preexisting biomarker representing a vulnerability factor for the development of PTSD. To that end, they determined whether the dexamethasone binding capacity of leukocytes, as a measure of glucocorticoidreceptor (GR) number, before exposure to trauma was a predictor of development of PTSD symptoms.

Pre-deployment differences in glucocorticoid sensitivity of leukocytes in soldiers developing symptoms of PTSD, depression or fatigue persist after return from military deployment

Deployed soldiers are at risk of developing stress-related conditions, including posttraumatic stress disorder (PTSD), major depressive disorder (MDD), and severe fatigue. We previously observed condition- and cell-specific differences in sensitivity of immune cells for regulation by glucocorticoids (GCs) pre-deployment between male soldiers with and without subsequent development of high levels of these stress-related symptoms. Here we investigated whether these pre-deployment dysregulations in GC-sensitivity of immune cells persisted after return from military deployment.

Posttraumatic stress: state of the art research and clinical implications for China

In a unique collaboration between The Seventh Hospitalof Hangzhou, the International Society forTraumatic Stress Studies (ISTSS), and the ZhejiangBehavior Medicine Association, the international conference‘‘Posttraumatic stress: state-of-the-art researchand clinical implications for China’’ was organized inHangzhou, China, on 17 19 October 2014.

Posttraumatic stress symptoms and health-related quality of life: a two year follow-up study of injury treated at the Emergency Department

BackgroundAmong injury victims relatively high prevalence rates of posttraumatic stress disorder (PTSD) have been found. PTSD is associated with functional impairments and decreased health-related quality of life (HRQoL). Previous studies that addressed the latter were restricted to injuries at the higher end of the severity spectrum. This study examined the association between PTSD symptoms and health-related quality of life (HRQoL) in a comprehensive population of injury patients of all severity levels and external causes.

Police officers: a high-risk group for the development of mental health disturbances? A cohort study

Objectives Policing is generally considered a high-risk profession for the development of mental health problems, but this assumption lacks empirical evidence. Research question of the present study is to what extent mental health disturbances, such as (very) severe symptoms of anxiety, depression and hostility are more prevalent among police officers than among other occupational groups. Design Multicomparative cross-sectional study using the data of several cross-sectional and longitudinal studies in the Netherlands.

Post-disaster psychosocial services across Europe: The TENTS project

At present post-disaster activities and plans seem to vary widely. An adequate estimation of the availability of post-disaster psychosocial services across Europe is needed in order to compare them with recently developed evidence-informed psychosocial care guidelines. Here we report on the results of a cross-sectional web-based survey completed in 2008 by two hundred and eighty-six representatives of organizations involved in psychosocial responses to trauma and disaster from thirty-three different countries across Europe.

Pharmacotherapy in the aftermath of trauma, opportunities in the 'golden hours'

Several lines of research have demonstrated that memories for fearful events become transiently labile upon re-exposure. Activation of molecular mechanisms is required in order to maintain retrieved information. This process is called reconsolidation. Targeting reconsolidation - as in exposure-based psychotherapy - offers therefore a potentially interesting tool to manipulate fear memories, and subsequently to treat disorders such as post-traumatic stress disorder (PTSD).

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