Background:
Ketamine has been used in anesthesia, pain management, and major depressive disorder. It has recently been studied in patients with post-traumatic stress disorder (PTSD).
 

Objective:
To determine the impact of ketamine on PTSD symptomatology and depression scores.
 

In this consensual qualitative research study, we investigated the role of refugees’ Christian faith in meaning-making coping. High percentages of religiosity in refugee populations support the need to understand the role of religion in their coping processes. Interviews with 20 Christian refugees from 10 African and Asian countries revealed that participants drew heavily from their faith resources to cope with their experiences.

Current evidence-based treatments for post-traumatic stress disorder (PTSD) are efficacious in only part of PTSD patients. Therefore, novel neurobiologically informed approaches are urgently needed. Clinical and translational neuroscience point to altered learning and memory processes as key in (models of) PTSD psychopathology. We extended this notion by clarifying at a meta-level (i) the role of information valence, i.e. neutral versus emotional/fearful, and (ii) comparability, as far as applicable, between clinical and preclinical phenotypes.

Achtergrond: Functionele MRI biedt inzicht in het functioneren van hersennetwerken van patiënten met psychiatrische stoornissen. Met machinelearninganalyse kunnen modellen worden gemaakt voor diagnostiek en het voorspellen van behandeluitkomst.

Doel: Een overzicht bieden van recente inzichten in diagnostische en voorspellende neuro-imagingbiomarkers.

Methode: Narratieve review van recente literatuur.

Achtergrond: Psychedelica kregen de afgelopen decennia hernieuwde wetenschappelijke aandacht omdat ze behalve acute subjectieve effecten, ook langdurige veranderingen in gedrag en cognitie teweeg kunnen brengen, met mogelijke therapeutische toepassingen bij verschillende psychiatrische indicaties.

Doel: Een overzicht geven van de huidige kennis over de neurobiologische werking van klassieke serotonerge psychedelica, zoals lsd en psilocybine, hun invloed op neurale netwerken en de gevolgen voor mogelijke klinische toepassingen.

De Nooit Meer Auschwitz lezing 2024 vindt plaats op woensdag 24 januari in Het Koninklijk Instituut voor de Tropen te Amsterdam. De lezing wordt (in het Engels) uitgesproken door historicus Nikita Petrov namens mensenrechtenorganisatie Memorial.
Aansluitend ontvangt Nikita Petrov de Annetje Fels Kupferschmidt Onderscheiding.
De zaal is open om 14:30 uur, de lezing begint om 15:00 uur en duurt tot 16:30 uur. Tot 18:00 uur is er gelegenheid om na te praten.

The application of MDMA in conjunction with psychotherapy has in recent years seen a resurgence of clinical, scientific, and public interest in the treatment of posttraumatic stress disorder (PTSD). Clinical trials have shown promising safety and efficacy, but the mechanisms underlying this treatment form remain largely unestablished. This article explores recent preclinical and clinical evidence suggesting that the treatment’s efficacy may be influenced by the mnemonic effects of MDMA.

There has been a resurgence in psychedelic research for managing psychiatric conditions in recent years.

This article delivers a comprehensive review of the English-language literature concerning the experiences of lesbian, gay, bisexual, transgender, transsexual, and queer (LGBTQ) refugees and asylum-seekers. Through an incisive synthesis and analysis, it identifies five pivotal themes: 1) journey and settlement; 2) legislation, policy, and charitable intervention; 3) health; 4) creative expression; and 5) religion, faith, and spirituality.

The multiple studies that have examined the transgenerational transmission of Holocaust trauma from survivors to their descendants have yielded inconsistent results. These can be attributed to differences in assessment tools and to individual differences between survivors, such as their specific experiences during the Holocaust.