Pharmacological memory modulation to augment trauma-focused psychotherapy for PTSD : a systematic review of randomised controlled trials

Trauma-focused psychotherapy (tf-PT) is the first-line treatment for posttraumatic stress disorder (PTSD). Tf-PT focuses on processing and modulating trauma memories. Not all patients benefit, however, and there is room for improvement of efficacy. Pharmacologically augmenting trauma memory modulation in the context of tf-PT may help optimise treatment outcome. To systematically review effects of pharmacologically augmented memory modulation in the context of tf-PT for PTSD (PROSPERO preregistration ID: CRD42021230623).


Historical Trauma and Cultural Scripts of Trauma among Trauma Survivors in Rwanda and East-Africa

Worldwide many people are exposed to natural disasters and man-made traumas that are known to have different short and long-term post traumatic consequences on their life. So far, Post-Traumatic Stress Disorders (PTSD) is the most well-known disorder shown by many scientists and clinicians as a result of aversive traumatic exposure. To date, its diagnostic criteria are well defined and different interventions have developed in many western countries.

Bereavement issues and prolonged grief disorder : A global perspective

The death of a loved one – bereavement – is a universal experience that marks the human mental health condition. Grief – the cognitive, emotional, and behavioral responses to bereavement – is thus experienced by virtually everyone at some point in life, while mourning is a process through which grievers come to terms with the loss envisioning life without the deceased. Although distress subsides over time among most bereaved individuals, a minority will develop a condition recently identified as prolonged grief disorder (PGD).


The structure of ICD-11 post traumatic stress disorder in a clinical sample of refugees based on the International Trauma Interview

The ICD-11 proposes fundamental changes to the PTSD diagnostic criteria, prompting thorough validation. While this is ideally carried out based on diagnostic interviews, most—and in the case of transcultural psychiatry all—studies have relied on self-reported measures. In this study, we used the International Trauma Interview (ITI) to assess the factor structure of ICD-11 PTSD symptoms in a sample of trauma-affected refugees.


Triadic Therapy Based on Somatic Eye Movement Desensitization and Reprocessing for Posttraumatic Stress Disorder : A Pilot Randomized Controlled Study

The triadic therapy based on somatic eye movement desensitization and reprocessing (EMDR) for posttraumatic stress disorder (TSP) is a combination therapy for complex posttraumatic stress disorder (cPTSD), which comprises simplified EMDR, triplet of micro-dose medicines, and a pair of Chinese medicines. The EMDR procedure is a tactile bilateral stimulation on the body surface with minimum verbal intervention within 15 minutes every 2 weeks in a period of 2–3 months.


War trauma impacts in Ukrainian combat and civilian populations : Moral injury and associated mental health symptoms

This is the first study to compare active-duty soldiers and student civilian samples during the first three months of the Ukrainian-Russian war in relation to moral injury and its association with PTSD, anxiety and depression.


Warning signals? An explorative study of distant recollections of the moments before a disaster

Background: How do we remember what happened shortly before a traumatic experience? There has been little focus on the temporal context of trauma memories, but a few studies suggest that aspects of what happened in the moments prior to a traumatic experience may be selectively enhanced and prioritized in memory.


Associations between trauma and substance use among healthcare workers and public safety personnel during the SARS-CoV-2 (COVID-19) pandemic : the mediating roles of dissociation and emotion dysregulation

Background: Given the highly stressful environment surrounding the SARS-CoV-2 pandemic, healthcare workers (HCW) and public safety personnel (PSP) are at an elevated risk for adverse psychological outcomes, including posttraumatic stress disorder (PTSD) and alcohol/substance use problems. As such, the study aimed to identify associations between PTSD severity, related dissociation and emotion dysregulation symptoms, and alcohol/substance use problems among HCWs and PSP.


Intergenerational associations of adverse and positive maternal childhood experiences with young children’s psychosocial well-being

Background: Maternal adverse childhood experiences (ACEs) are believed to have negative consequences on offspring health. However, positive childhood experiences (PCEs) may be concurrent with ACEs, and little is known about how ACEs and PCEs transmit intergenerationally in the context of each other.


Objective: To explore the independent effect of maternal ACEs and PCEs on offspring psychosocial well-being and how ACEs and PCEs are intergenerationally transmitted in their context.


Shame, depression, and complicated grief among suicide loss-survivors : the moderating role of self-disclosure

Background: Suicide-loss survivors (SLSs) are recognised as an at-risk population for several psychiatric complications, including complicated grief (CG) and depression (SI). However, whereas shame is known as one of the characteristics of this population, knowledge about possible psychological processes which may moderate the contribution of shame levels to CG and depression in the aftermath of suicide loss is sparse.