3,4-methylenedioxymethamphetamine (MDMA)-assisted psychotherapy for post-traumatic stress disorder in military veterans, firefighters, and police officers : a randomised, double-blind, dose-response, phase 2 clinical trial

Summary

 

Background

Post-traumatic stress disorder (PTSD) is prevalent in military personnel and first responders, many of whom do not respond to currently available treatments. This study aimed to assess the efficacy and safety of 3,4-methylenedioxymethamphetamine (MDMA)-assisted psychotherapy for treating chronic PTSD in this population.

 

Methods

Posttraumatic stress disorder related to postpartum haemorrhage : A systematic review

In some cases childbirth leads to negative psychological responses such as posttraumatic stress disorder (PTSD). Postpartum hemorrhage (PPH) is a common and major complication of childbirth, which occasionally requires emergency hysterectomy in severe cases. Patients often describe these complications as a traumatic experience. It is unknown whether PPH is a risk factor for developing PTSD.

An innovative framework for delivering psychotherapy to patients with treatment-resistant posttraumatic stress disorder : Rationale for interactive motion-assisted therapy

Despite an array of evidence-based psychological treatments for patients with a posttraumatic stress disorder (PTSD), a majority of patients do not fully benefit from the potential of these therapies. In veterans with PTSD, up to two-thirds retain their diagnosis after psychotherapy and often their disorder is treatment-resistant, which calls for improvement of therapeutic approaches for this population. One of the factors hypothesized to underlie low response in PTSD treatment is high behavioral and cognitive avoidance to traumatic reminders.

Assessing psychological resilience : Development and psychometric properties of the English and Dutch version of the Resilience Evaluation Scale (RES)

Background: Psychological resilience is a distinct factor that affects mental health outcomes after adversities. This study describes the development, validity and measurement invariance (MI) of a Dutch and English scale on psychological resilience, called the Resilience Evaluation Scale (RES).

 

Methods: Separate online surveys with the Dutch and English version of the RES and hypothesized relatedmeasures were distributed in a Dutch- and English-speaking group, both drawn from the general population.

 

Neurocognitive functioning over the course of trauma-focused psychotherapy for ptsd : Changes in verbal memory and executive functioning

Objectives

Individuals with post‐traumatic stress disorder (PTSD) have neurocognitive deficits in verbal memory and executive functioning. In this study, we examined whether memory and executive functioning changed over the course of treatment and which clinical variables were associated with change.

Design

Neuropsychological assessments were administered at baseline and endpoint of a randomized controlled trial as secondary outcome.

Methods

Moving forward in treatment of posttraumatic stress disorder : innovations to exposure-based therapy

The field of treatment of posttraumatic stress disorder (PTSD) has been a pacesetter for the changing face of psychotherapy, as is illustrated in the introduction of Virtual Reality Exposure Therapy. This paper outlines a novel approach that builds on a cognitive-motor interaction in a virtual interactive environment. It is based on the theory of memory reconsolidation and the embodiment of cognition.

Latent class analysis of indicators of intolerance of uncertainty

Intolerance of Uncertainty (IU) is a transdiagnostic vulnerability factor involved in depression and anxiety symptoms and disorders. IU encompasses Prospective IU (“Unforeseen events upset me greatly”) and Inhibitory IU (“The smallest doubt can stop me from acting”). Research has yet to explore whether subgroups or classes of people exist characterized by different profiles of IU.

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