Impaired learning, memory, and extinction in posttraumatic stress disorder : translational meta-analysis of clinical and preclinical studies

Current evidence-based treatments for post-traumatic stress disorder (PTSD) are efficacious in only part of PTSD patients. Therefore, novel neurobiologically informed approaches are urgently needed. Clinical and translational neuroscience point to altered learning and memory processes as key in (models of) PTSD psychopathology. We extended this notion by clarifying at a meta-level (i) the role of information valence, i.e. neutral versus emotional/fearful, and (ii) comparability, as far as applicable, between clinical and preclinical phenotypes.

Read more

Efficacy and Safety of Four Psychedelic-Assisted Therapies for Adults with Symptoms of Depression, Anxiety, and Posttraumatic Stress Disorder : A Systematic Review and Meta-Analysis

There has been a resurgence in psychedelic research for managing psychiatric conditions in recent years.

 

Read more

Critiquing Trends and Identifying Gaps in the Literature on LGBTQ Refugees and Asylum-Seekers

This article delivers a comprehensive review of the English-language literature concerning the experiences of lesbian, gay, bisexual, transgender, transsexual, and queer (LGBTQ) refugees and asylum-seekers. Through an incisive synthesis and analysis, it identifies five pivotal themes: 1) journey and settlement; 2) legislation, policy, and charitable intervention; 3) health; 4) creative expression; and 5) religion, faith, and spirituality.

 

Read more

Holocaust communication, attachment orientation and distress among descendants of female holocaust survivors

The multiple studies that have examined the transgenerational transmission of Holocaust trauma from survivors to their descendants have yielded inconsistent results. These can be attributed to differences in assessment tools and to individual differences between survivors, such as their specific experiences during the Holocaust.

 

Read more

Routledge International Handbook of Multidisciplinary Perspectives on Descendants of Holocaust Survivors

The Routledge International Handbook of Multidisciplinary Perspectives on Descendants of Holocaust Survivors offers a comprehensive collection of cutting-edge studies from a wide range of fields dealing with new research about descendants of Holocaust survivors. Examining the aftermath of the Holocaust on the Second Generation and Third Generation, children and grandchildren of Holocaust survivors, it is the first volume to bring together research perspectives from history, psychology, sociology, communications, literature, film, theater, art, music, biology, and medicine.

Read more

Unity or Anarchy? : A Historical Search for the Psychological Consequences of Psychotrauma

The field of traumatic stress is often referred to as being in a state of controversy and lack of continuity. Throughout history, disputes repeatedly centered on defining the psychological consequences of severe adverse events and on their causes. Even to this day this is current. To understand these controversies, an extensive historical literature review is presented of how mental consequences of trauma have been described in history, of the circumstances in which this took place, and of the disputes that have influenced the conceptualization of these mental responses.

 

Read more

Functional brain changes after alternative pharmacological interventions in posttraumatic stress disorder : A systematic review of clinical trials

Background
Posttraumatic stress disorder (PTSD) is a complex and heterogeneous mental health condition that can develop after exposure to a traumatic event. Clinical trials have used alternative pharmacological agents to treat PTSD, but their associated neural correlates remain unclear. The present systematic review aims to summarize the changes in brain function associated with the use of these alternative pharmacological agents in PTSD.

Read more

How does it feel?: An exploration of neurobiological and clinical correlates of alexithymia in trauma-exposed police-officers with and without PTSD

Background: Alexithymia, an inability to recognise one’s emotions, has been associated with trauma-exposure and posttraumatic stress disorder (PTSD). Previous research suggests involvement of the oxytocin system, and socio-emotional neural processes. However, the paucity of neurobiological research on alexithymia, particularly in trauma-exposed populations, warrants further investigation.

Objective: Explore associations between alexithymia, endogenous oxytocin levels, and socio-emotional brain function and morphometry in a trauma-exposed sample.

Read more

Factors associated with mental health of young children during the COVID-19 pandemic in the Netherlands

Background
The COVID-19 pandemic and accompanying societal measures have impacted children and their families all over the world. Little is known about the factors associated with mental health outcomes in young children (i.e., 1 to 6 years old) during the pandemic. The current study aimed to examine associations with potential risk and protective factors, i.e., direct COVID-19 exposure factors as well as within-family characteristics.

Read more

The effect of individual characteristics on susceptibility to aggressive and/or intimidating approaches : quantifying probability pathways by creating a victimization model

Background: A significant body of literature has identified multiple factors that contribute to established victimization by aggressive and/or intimidating behaviours. These studies primarily originate from the fields of intimate partner violence (IPV), bullying, sexual abuse, and/or commercial sexual exploitation (CSE), and generally focus on female victims. It appears, however, complicated to quantify the cumulative contribution of these factors on susceptibility to intimidating and/or hostile engagements on an individual level.

Read more

Pages