A systematic review of the incidence of medical serious adverse events in sub-anesthetic ketamine treatment of psychiatric disorders

Background
Limited published data exists that collates serious adverse outcomes involving ketamine as a psychiatric intervention. This systematic review assesses the reported incidence of medical serious adverse events (MSAEs), including but not limited to cardiovascular events, in patients receiving sub-anesthetic doses of ketamine for psychiatric disorders to guide practitioners during treatment planning, risk-benefit analyses, and the informed consent process.

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Do savoring beliefs predict posttraumatic stress symptoms following stressful life events?

Background and objectives: Savoring beliefs refer to people’s beliefs about their ability to generate, increase, and prolong enjoyment from positive experiences. The role of these beliefs in affecting responses to negative events is largely unexplored. This study aimed to increase
knowledge about the role of savoring beliefs in symptoms of posttraumatic stress (PTS) following negative life events and the incremental role of these beliefs beyond the impact of worry, depressive rumination, and neuroticism.

 

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Treatment of Posttraumatic Stress Disorder : A State-of-the-art Review

This narrative state-of-the-art review paper describes the progress in the understanding and treatment of Posttraumatic Stress Disorder (PTSD). Over the last four decades, the scientific landscape has matured, with many interdisciplinary contributions to understanding its diagnosis, etiology, and epidemiology. Advances in genetics, neurobiology, stress pathophysiology, and brain imaging have made it apparent that chronic PTSD is a systemic disorder with high allostatic load.

 

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Perspectives on dying in severe and enduring eating disorders (SEEDs) : A qualitative study among Dutch mental healthcare providers

Dying of severe and enduring eating disorders (SEEDs) was studied using semi-structured interviews (n=7) and a follow-up videoconferencing focus group (n=3) with Dutch mental healthcare providers. We identified three main themes: the uncertainties of dying from SEEDs, dilemmas in defining treatment resistance and palliative care, and suicidal ideation and intent.

 

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Smaller total and subregional cerebellar volumes in posttraumatic stress disorder : a mega-analysis by the ENIGMA-PGC PTSD workgroup

Although the cerebellum contributes to higher-order cognitive and emotional functions relevant to posttraumatic stress disorder (PTSD), prior research on cerebellar volume in PTSD is scant, particularly when considering subregions that differentially map on to motor, cognitive, and affective functions.

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Best Practice Injury Compensation Processes Following Intentional Vehicular Assaults and Other Large Scale Transport Incidents : A Delphi Review

Objective:
Intentional vehicular assaults on civilians have become more frequent worldwide, with some resulting in mass casualties, injuries, and traumatized witnesses. Health care costs associated with these vehicular assaults usually fall to compensation agencies. There is, however, little guidance around how compensation agencies should respond to mental and physical injury claims arising from large-scale transport incidents.

Methods:

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Morally injurious events and depression : Examining the role of rumination among combat-deployed military veterans in the community

While depression remains a common psychological disorder among combat military veterans, there is a need to investigate factors that relate to the development and maintenance of this disorder. Potentially morally injurious events (PMIEs), perceived transgressions against one’s moral code, are associated with depression. This relationship may be influenced by the level of engagement in brooding rumination.

 

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The role of guilt-shame proneness and locus of control in predicting moral injury among healthcare professionals

Despite the advances in studies conducted among healthcare professionals to explore the impact of the pandemic on their mental health, a large population still continues to display COVID-19 related psychological complaints. There has been recent awareness of moral injury related guilt and shame among doctors and nurses. However, the factors associated with moral injury have not received much attention, due to which the issue still persists. This study aims to explore the role of guilt-shame proneness, and locus of control in predicting moral injury among healthcare professionals.

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Examining moral injury in clinical practice : A narrative literature review

Healthcare workers experience moral injury (MI), a violation of their moral code due to circumstances beyond their control. MI threatens the healthcare workforce in all settings and leads to medical errors, depression/anxiety, and personal and occupational dysfunction, significantly affecting job satisfaction and retention.

 

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Moral injury and its mental health consequences among protesters : findings from Israel’s civil protest against the government's judicial reform

Background: Government actions and participating in protracted-duration protests against it affect protesters' mental health, leading to high distress levels, such as posttraumatic and depressive symptoms. Aside from exposure to violence and other issues, protest participation can pose unique challenges to the protesters as they may be exposed to potentially morally injurious events (PMIEs), such as the betrayal of leaders they once trusted.

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