Strong memory of a traumatic event is thought to contribute to the development and symptoms of posttraumatic stress disorder (PTSD). Therefore, a genetic predisposition to build strong memories could lead to increased risk for PTSD after a traumatic event. Here we show that genetic variability of the gene encoding PKC? (PRKCA) was associated with memory capacity-including aversive memory-in nontraumatized subjects of European descent. This finding was replicated in an independent sample of nontraumatized subjects, who additionally underwent functional magnetic resonance imaging (fMRI).

Hoe is de biografie van verzetsheld Pim Boellaard te benutten voor overdracht en educatie? Het antwoord ligt besloten in het verhaal van zijn leven. Maurits Nibbering, voormalig directeur van Nationaal Monument Kamp Amersfoort, pleit voor meer studies als die over Boellaard. Ze zijn onmisbaar voor educatie op een herinneringsplek als Kamp Amersfoort.

The general aim of this thesis was to examine how nurses can use photography to assist psychiatric patients in making meaning of experiences of illness and to help them in the process of recovery. The study is based on a hermeneutic-phenomenological perspective, focusing on processes of experiencing and meaning making in the life world. Existential issues, e.g. the way how people give meaning to their suffering, play an important role in this process of being-in-the world.

Several lines of research have demonstrated that memories for fearful events become transiently labile upon re-exposure. Activation of molecular mechanisms is required in order to maintain retrieved information. This process is called reconsolidation. Targeting reconsolidation - as in exposure-based psychotherapy - offers therefore a potentially interesting tool to manipulate fear memories, and subsequently to treat disorders such as post-traumatic stress disorder (PTSD).

Aggressive behaviour is an important problem in mental health care. Aggressive behaviour does not only affect staff and other patients, but also has a negative impact on the patient self. Studies have shown that aggressive patients have a longer stay on psychiatric wards compared to non-aggressive patients. In psychiatric wards, several interventions are used to manage aggressive behaviour. In the Netherlands, seclusion has for decades been a highly common intervention to manage (imminent) aggression. During recent years, however, the use of seclusion has been heavily criticized.

Het psychobiologisch persoonlijkheidsmodel ontwikkeld door Cloninger omvat vier dimensies van temperament en drie dimensies van karakter. Studies hebben aangetoond dat deze persoonlijkheidsdimensies verschillen tussen patiënten die lijden aan een depressie en controlepersonen zonder depressie.
doel: Nagaan of er verschillen bestaan in persoonlijkheidskenmerken tussen personen die in het verleden een depressieve episode doormaakten en daarvan volledig herstelden, en personen die nooit depressief geweest zijn.

Aim of the present three-wave study was to examine to what extent personality traits and general self-efficacy measured before exposure to a potentially traumatic event (PTE) prospectively predict coping self-efficacy (CSE) perceptions, and to test whether outcomes are biased by the timing of assessment of personality traits. The study was conducted within a large probability-based multi-wave representative internet panel in the Netherlands (Ntotal = 1154)

Personality Disorders: Theory, Research, and Treatment ® (PD:TRT) publishes a wide range of cutting edge research on personality disorders and related psychopathology from a categorical and/or dimensional perspective including laboratory and treatment outcome studies, as well as integrative conceptual manuscripts and practice reviews that bridge science and practice.

AIM: Although some studies have examined the long-term effects of disasters, very little is known about severe persistent symptoms following disasters. The aim of the present study was to examine persistent mental health problems and to what extent disaster exposure predicts long-term persistent disturbances.

Background: Stress sensitization, i.e., increased responsiveness to stressful life events has been found in high trauma exposed adults within the first 18 months following trauma exposure (Smid et al., 2012) as well as in young children (Grasso, Ford, & Briggs-Gowan, 2012). However, it is unclear whether stress sensitization may persist over time. We hypothesized that soldiers exposed to high levels of early life trauma would be at risk of persistence of stress sensitization 2 years following deployment.