Prolonged exposure and EMDR for PTSD v. a PTSD waiting-list condition : effects on symptoms of psychosis, depression and social functioning in patients with chronic psychotic disorders

In patients with psychotic disorders, the effects of psychological post-traumatic stress disorder (PTSD) treatment on symptoms of psychosis, depression and social functioning are largely unknown

The factor structure of complex posttraumatic stress disorder in traumatized refugees

Background
The construct of complex posttraumatic stress disorder (CPTSD) has attracted much research attention in previous years, however it has not been systematically evaluated in individuals exposed to persecution and displacement. Given that CPTSD has been proposed as a diagnostic category in the ICD-11, it is important that it be examined in refugee groups.
Objective
In the current study, we proposed to test, for the first time, the factor structure of CPTSD proposed for the ICD-11 in a sample of resettled treatment-seeking refugees.

“I can’t tell whether it’s my hand” : a pilot study of the neurophenomenology of body representation during the rubber hand illusion in trauma-related disorders

Background: Early traumatic experiences are thought to be causal factors in the development of trauma-related dissociative experiences, including depersonalization and derealization. The rubber hand illusion (RHI), a well-known paradigm that measures multi-sensorial integration of a rubber hand into one’s own body representation, has been used to investigate alterations in the experience of body ownership and of body representation. Critically, however, it has never been studied in individuals with trauma-related disorders.

Investigating epigenetic consequences of early-life adversity : some methodological considerations

Stressful and traumatic events occurring during early childhood have been consistently associated with the development of psychiatric disorders later in life. This relationship may be mediated in part by epigenetic mechanisms, such as DNA methylation, which are influenced by the early-life environment. Epigenetic patterns can have lifelong effects on gene expression and on the functioning of biological processes relevant to stress reactivity and psychopathology.

PTSD : from neurobiology to pharmacological treatments

Posttraumatic stress disorder (PTSD) is a chronic debilitating psychiatric disorder characterized by symptoms of re-experience, avoidance, and hyperarousal that can arise immediately or many years after exposure to a traumatic event and injury. Although extensive research has been done over the past 30 years, the etiology of PTSD remains largely unknown. Several neurobiological systems have been implicated in the pathophysiology and vulnerability for developing PTSD; however, first-line pharmacotherapies are limited.

A review of research on moral injury in combat veterans

The moral injury construct has been proposed to describe the suffering some veterans experience when they engage in acts during combat that violate their beliefs about their own goodness or the goodness of the world. These experiences are labeled transgressive acts to identify them as potentially traumatic experiences distinct from the fear-based traumas associated with posttraumatic stress disorder.

Biological profiling of plasma neuropeptide Y in relation to posttraumatic stress symptoms in two combat cohorts

Military personnel have an increased risk of developing stressrelated mental health problems after deployment to a combat zone [1]. In order to decrease the risk of developing stress-related disorders, biological vulnerability and protective factors should be identified. Neuropeptide Y (NPY) is a peptide transmitter that is associated with modulation of the stress response. Previous studies reported reduced NPY levels in the cerebrospinal fluid (CSF) of patients with posttraumatic stress disorder (PTSD) [2].

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