Perceived treatment processes and effects of interactive motion-assisted exposure therapy for veterans with treatment-resistant posttraumatic stress disorder : a mixed methods study

Background: A novel intervention, Multi-modular motion-assisted memory desensitization and reconsolidation (3MDR), aims to reduce avoidance and improve engagement for patients with posttraumatic stress disorder (PTSD) who did not sufficiently respond to previous treatments. It has been found to effectively reduce PTSD symptoms for veterans with treatment-resistant PTSD. Symptomatic measures alone might not capture all treatment effects, and addition of qualitative outcomes may provide deeper understanding of treatment processes and treatment-induced changes.

 

The relationship between potentially traumatic or stressful events, HIV infection and neurocognitive impairment (NCI) : a systematic review of observational epidemiological studies

Background: HIV/AIDS and potentially traumatic events (PTEs) or stressful life events (SLEs) and/or PTSD are independently associated with neurocognitive impairment (NCI). Literature suggests that HIV and PTE/SLE exposure independently and consistently affect various domains of cognition including language ability, working memory and psychomotor speed. There are limited data on the interaction between HIV infection and PTEs and their combined effect on NCI.

Genetic predictors of hippocampal subfield volume in PTSD cases and trauma-exposed controls

Behavioural, structural, and functional neuroimaging have implicated the hippocampus as a critical brain region in posttraumatic stress disorder (PTSD) pathogenesis. Recent work in a normative, primarily European, sample identified 15 unique genetic loci contributing to structural variability in six hippocampal subfield volumes. We explored the relevance of these loci in two samples (Mental Illness Research Education and Clinical Centre [MIRECC] and Grady; n = 290) of trauma-exposed individuals enriched for PTSD and of diverse ancestry.

 

Sexual function and pelvic floor activity in women : the role of traumatic events and PTSD symptoms

Background: Traumatic sexual experiences can negatively affect sexual functioning and increase pelvic floor activity in women, especially when post-traumatic stress disorder (PTSD) is developed. However, little is known about the effect of other types of interpersonal and non-interpersonal, traumatic experiences on sexual function and pelvic floor overactivity. 

PTSD-Repository

The PTSD Trials Standardized Data Repository (PTSD-Repository) is a database that contains hundreds of variables extracted from more than 300 published randomized controlled clinical trials of PTSD treatment. The data in PTSD-Repository are free to use without restriction.

 

 

Access a growing set of featured visualizations or easily create custom maps and graphs. Download data in a variety of formats for use offline or filter data within the site itself.

Sleep disturbances and nightmares in victims of sexual abuse with post-traumatic stress disorder : an analysis of abuse-related characteristics

Background: Sexual abuse victims often experience symptoms of post-traumatic stress disorder (PTSD), including sleep disturbances.

 

Objective: To investigate whether or not characteristics of sexual abuse are associated with sleep disturbance, and to explore whether correlates of sleep disturbance are distinguishable from those of PTSD symptom severity.

 

Applying machine learning on health record data from general practitioners to predict suicidality

Background: Suicidal behaviour is difficult to detect in the general practice. Machine learning (ML) algorithms using routinely collected data might support General Practitioners (GPs) in the detection of suicidal behaviour. In this paper, we applied machine learning techniques to support GPs recognizing suicidal behaviour in primary care patients using routinely collected general practice data.

 

Economic evaluations and cost analyses in posttraumatic stress disorder : a systematic review

Background

 

Posttraumatic stress disorder is associated with a high economic burden. Costs of treatment are known to be high, and cost-effectiveness has been analysed for several treatment options.

 

Objective

 

As no review on economic aspects of posttraumatic stress disorder exists, the aim of this study was to systematically review costs-of-illness studies and economic evaluations of therapeutic treatment for posttraumatic stress disorder, and to assess their quality.

 

Method

Anxiety, depression and post-traumatic stress disorder in refugees resettling in high-income countries : systematic review and meta-analysis

Background
The number of refugees is at its highest since the Second World War and on the rise. Many refugees suffer from anxiety, depression and post-traumatic stress disorder (PTSD), but exact and up-to-date prevalence estimates are not available.

Aims
To report the pooled prevalence of anxiety and mood disorders and PTSD in general refugee populations residing in high-income countries and to detect sources of heterogeneity therein.

Method
Systematic review with meta-analyses and meta-regression.

Pages