Is Post-Traumatic Stress Disorder Associated with Premature Senescence

Objective Post-traumatic stress disorder (PTSD) has major public health significance. Evidence that PTSD may be associated with premature senescence (early or accelerated aging) would have major implications for quality of life and healthcare policy. We conducted a comprehensive review of published empirical studies relevant to early aging in PTSD.

Pharmacotherapy for post-traumatic stress disorder: systematic review and meta-analysis

Abstract
Background
Pharmacological treatment is widely used for post-traumatic stress disorder (PTSD) despite questions over its efficacy.
Aims
To determine the efficacy of all types of pharmacotherapy, as monotherapy, in reducing symptoms of PTSD, and to assess acceptability.
Method
A systematic review and meta-analysis of randomised controlled trials was undertaken; 51 studies were included.
Results

The efficacy of recommended treatments for veterans with PTSD : A metaregression analysis

Soldiers and veterans diagnosed with PTSD benefit less from psychotherapy than nonmilitary populations. The current meta-analysis identified treatment predictors for traumatised soldiers and veterans, using data from studies examining guideline recommended

Predictors of posttraumatic stress and appetitive aggression in active soldiers and former combatants

Abstract
Background: During the period between 1993 and 2005, the people of Burundi were trapped within a violent civil war. In post-conflict regions, symptoms of posttraumatic stress disorder (PTSD) were found to be widespread. At the same time, combatants often reported having perceived committing violence as exciting and appealing, an experience referred to as appetitive aggression. Both of these phenomena hamper the building of a functional and peaceful society.

Pharmacological prevention of post-traumatic stress disorder and acute stress disorder: a systematic review and meta-analysis

Summary
Background
An increasing number of studies have investigated the pharmacological prevention of post-traumatic stress disorder (PTSD) and acute stress disorder (ASD). This is the first systematic review to examine the effects of pharmacotherapies (eg, β blockers, hydrocortisone, and selective serotonin re-uptake inhibitors) given within the first month after a traumatic or aversive event to prevent PTSD or ASD compared with no pharmacotherapy or placebo control.
Methods

Aging Holocaust Survivors Still Suffer From PTSD

From 1942 to 1945, Sonia Reich, a pre-adolescent Jew, was on the run. Orphaned and alone, she fought to keep herself alive while the majority of her extended family was executed in the Holocaust. When World War II ended, Sonia came to the United States, married a Holocaust survivor and built what her son, Howard, calls “the American Dream": a long marriage, children and grandchildren who went to college, a house without a mortgage, a car, and an extended life. From the outside, it seemed that Sonia had escaped the camps.

Latent profile analysis and principal axis factoring of the DSM-5 dissociative subtype

Abstract
Objective: A dissociative subtype has been recognized based on the presence of experiences of depersonalization and derealization in relation to DSM-IV posttraumatic stress disorder (PTSD). However, the dissociative subtype has not been assessed in a community sample in relation to the revised DSM-5 PTSD criteria. Moreover, the 20-item PTSD Checklist for DSM-5 (PCL-5) currently does not assess depersonalization and derealization.

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