Life events and depression in a community sample of siblings.

Abstract

BACKGROUND:

The overall aim of the GENESiS project is to identify quantitative trait loci (QTLs) for anxiety/depression, and to examine the interaction between these loci and psychosocial adversity. Here we present life-events data with the aim of clarifying: (i) the aetiology of life events as inferred from sibling correlations; (ii) the relationship between life events and measures of anxiety and depression, as well as neuroticism; and (iii) the interaction between life events and neuroticism on anxiety/depression indices.

METHODS:

Medically unexplained symptoms in frequent attenders of secondary health care: retrospective cohort study.

Abstract

OBJECTIVE:

To estimate the prevalence of medically unexplained symptoms in patients who most frequently attend outpatient services.

DESIGN:

Retrospective cohort study over three years with review of case notes.

SETTING:

Secondary care services in the South Thames (West) NHS region.

PARTICIPANTS:

Outpatient attenders with new appointments in 1993.

MAIN OUTCOME MEASURES:

Number of outpatient appointments, and number of consultation episodes for medically unexplained conditions.

RESULTS:

Incidence and prediction of posttraumatic stress disorder symptoms in severely injured accident victims.

Abstract

OBJECTIVE:

This study was designed to assess the incidence of posttraumatic stress disorder (PTSD) in severely injured accident victims and to predict the presence of PTSD symptoms at a 12-month follow-up.

METHOD:

Individual predictors of posttraumatic distress: a structural equation model.

Abstract

OBJECTIVE:

Recent research has called into question the "dose-effect" model of understanding response to trauma and has turned attention to the contribution of personality and environmental factors. This research seeks to model the interrelation of relational capacity (a component of personality), perceptions of social support, and posttraumatic distress.

METHOD:

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