MicroRNAs in Post-traumatic Stress Disorder

Post-traumatic stress disorder (PTSD) is a psychiatric disorder that can develop following exposure to or witnessing of a (potentially) threatening event.

A critical issue is to pinpoint the (neuro)biological mechanisms underlying the susceptibility to stress-related disorder such as PTSD, which develops in the minority of ~15% of individuals exposed to trauma. Over the last few years, a first wave of epigenetic studies has been performed in an attempt to identify the molecular underpinnings of the long-lasting behavioral and mental effects of trauma exposure.

Integrating NIMH Research Domain Criteria (RDoC) into PTSD Research

Three and a half decades of research on posttraumatic stress disorder (PTSD) has produced substantial knowledge on the pathobiology of this frequent and debilitating disease. However, despite all research efforts, so far no drug that has specifically targeted PTSD core symptoms progressed to clinical use. Instead, although not overly efficient, serotonin re-uptake inhibitors continue to be considered the gold standard of PTSD pharmacotherapy.

Children and natural disasters

The number of children affected by natural disasters each year is alarmingly high and can be expected to rise as climate change continues. The mental consequences have been documented not only in the rates of post-traumatic stress symptoms and post-traumatic stress disorder, but also for depression and other mental health problems.

Developing a culturally sensitive mental health intervention for asylum seekers in the Netherlands : a pilot study

Introduction: This pilot study investigated asylum seekers’ needs and expectations in the mental health field to develop a culturally sensitive psychosocial intervention.

 

Method: Participants were residents of a certain asylum-seekers centre in the Netherlands, with most of them from the Middle East crisis. Needs and expectations were identified using therapy expectations questionnaire (11 participants) and two focus groups (17 participants).

 

New targets for behaviour change in Ebola outbreaks : ideas for future interventions

Ebola virus disease (EVD) is an infectious disease with serious individual health and population consequences. While Ebola is extremely contagious, the 2014 outbreak in West Africa was the worst to date. Many strategies were implemented for the containment and treatment of the disease, although some were limited by a lack of focus on social and behavioural factors.

Rampsporen = Traces of Disaster

Disasters are unforgettable events. Or so we think. But what if the people directly involved are gone, where does the memory of such events reside? And how is this memory accessed? On this site, we invite you to explore with us, students from the University of Amsterdam, how previous disasters in the Netherlands left their trace on the Dutch cultural landscape. What practices of memorialization exist? Is it easy to recognize the event years later, when make our way through these same locations? And when encountering these traces, how do we react and experience these places?

New targets for behaviour change in Ebola outbreaks : Ideas for future interventions

Ebola virus disease (EVD) is an infectious disease with serious individual health and population consequences. While Ebola is extremely contagious, the 2014 outbreak in West Africa was the worst to date. Many strategies were implemented for the containment and treatment of the disease, although some were limited by a lack of focus on social and behavioural factors. These factors must be taken into consideration during intervention development at the levels of individuals, communities and international networks to address issues that could block intervention success.

Integrating psychosocial support at Ebola treatment units in Sierra Leone and Liberia

The Ebola virus disease (EVD) epidemic killed almost 12,000 people across Sierra Leone, Liberia and Guinea, causing significant psychological distress and suffering. This paper describes International Medical Corps’ innovative and comprehensive model for integrating mental health and psychosocial support (MHPSS) considerations and activities into Ebola treatment units (ETUs) across Sierra Leone and Liberia. This includes staff capacity building as well as psychosocial considerations and activities to address needs and challenges at the ETUs.

Children ‘disappeared’ at the United States/Mexico border : a symptom with consequences for the United States

‘Disappearing’ people as an act of torture has an ordinary language meaning, such that the United Nations could describe it and various torture treatment centres that address it as torture. The present United States policy of separating families into different prisons at its border with Mexico results in many such disappearances, and therefore is torture of both children and the families they are separated from. This article follows the United Nations description.

Prevalence of depression and posttraumatic stress disorder in adult civilian survivors of war who stay in war-afflicted regions : A systematic review and meta-analysis of epidemiological studies

 

Background: Epidemiological surveys on depression and posttraumatic stress disorder (PTSD) among civilian war survivors in war-afflicted regions have produced heterogeneous prevalence estimates of these conditions.

 

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