Objective: Post-traumatic stress disorder (PTSD) has major public health significance.
Evidence that PTSD may be associated with premature senescence (early or accelerated
aging) would have major implications for quality of life and healthcare policy.
We conducted a comprehensive review of published empirical studies relevant to
early aging in PTSD. Method: Our search included the PubMed, PsycINFO, and PILOTS
databases for empirical reports published since the year 2000 relevant to early