Traumatic stress and accelerated DNA methylation age : A meta-analysis

Abstract

 

 

Background

Recent studies examining the association between posttraumatic stress disorder (PTSD) and accelerated aging, as defined by DNA methylation-based estimates of cellular age that exceed chronological age, have yielded mixed results.

Methods

Finding a new narrative : Meaningful responses to ‘false memory’ disinformation

This chapter draws from George Monbiot’s (2017) thoughts on the political power of storytelling. He emphasizes that stories function as schema through which people organize information and develop a sense of order and purpose. It is a mistake, he warns, to try to rely on data to challenging a misleading story since ‘[t]he only thing that can displace a story is a story’ (Monbiot, 2017, p 3). In short, information is not sufficient to challenge disinformation: we must also supply a meaningful framework in which that information makes sense.

Development and Evaluation of the Thinking About Recovery Scale : Measure of Parent Posttraumatic Cognitions Following Children's Exposure to Trauma

Researchers have recently suggested that parent posttraumatic appraisals potentially contribute to the development of posttraumatic stress in both parents and children following children's exposure to trauma. However, a single‐instrument, multidimensional measure of parent posttraumatic cognitions as they relate to their child's recovery has yet to be operationalized.

Mental Health Problems Among Whistleblowers: A Comparative Study

Whistleblowers play a very important and indispensable role in society and health care sector, but their act may elicit retaliation and other negative effects, which may impact their mental health.

Resolving the vulnerability paradox in the cross-national prevalence of posttraumatic stress disorder

Socioeconomically disadvantaged individuals are at heightened risk for developing posttraumatic stress disorder (PTSD) following exposure to trauma. Yet a study of cross-national lifetime prevalence rates of PTSD revealed that countries scoring high on an index reflecting cultural and socioeconomic disadvantage exhibited lower rates of PTSD in response to trauma, evincing what the authors called “a vulnerability paradox in the cross-national prevalence of post-traumatic stress disorder” Dückers, Alisic, & Brewin (2016a, p. 300).

Early indicators of problematic grief trajectories following bereavement

ABSTRACT

 

Background: Little is known about the development of Prolonged Grief Disorder (PGD) symptoms over time in adults. For clinical purposes, it would be useful to have knowledge about early indicators of a problematic grief trajectory.

 

Objective: This study aimed to identify classes of bereaved individuals with similar trajectories of PGD symptoms and to design a provisional screening tool including symptoms predicting membership of classes with problematic grief trajectories.

DNA methylation as a mediator of the association between prenatal adversity and risk factors for metabolic disease in adulthood

Although it is assumed that epigenetic mechanisms, such as changes in DNA methylation (DNAm), underlie the relationship between adverse intrauterine conditions and adult metabolic health, evidence from human studies remains scarce. Therefore, we evaluated whether DNAm in whole blood mediated the association between prenatal famine exposure and metabolic health in 422 individuals exposed to famine in utero and 463 (sibling) controls.

Psychological Stress and Mitochondria : A Systematic Review

Objective Mitochondria are multifunctional life-sustaining organelles that represent a potential intersection point between psychosocial experiences and biological stress responses. This article provides a systematic review of the effects of psychological stress on mitochondrial structure and function.

Potentially traumatic events have negative and positive effects on loneliness, depending on PTSD-symptom levels : evidence from a population-based prospective comparative study

Abstract

 

Purpose Examine to what extent adults affected by recent potentially traumatic events (PTE) with different PTSD-symptom levels are more at risk for post-event loneliness than non-affected adults are in the same study period.

 

Smaller Hippocampal Volume in Posttraumatic Stress Disorder : A Multisite ENIGMA-PGC Study: Subcortical Volumetry Results From Posttraumatic Stress Disorder Consortia

Background

Many studies report smaller hippocampal and amygdala volumes in posttraumatic stress disorder (PTSD), but findings have not always been consistent. Here, we present the results of a large-scale neuroimaging consortium study on PTSD conducted by the Psychiatric Genomics Consortium (PGC)–Enhancing Neuroimaging Genetics through Meta-Analysis (ENIGMA) PTSD Working Group.

Methods

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