Psychedelic Treatments for Psychiatric Disorders : A Systematic Review and Thematic Synthesis of Patient Experiences in Qualitative Studies

Introduction

Interest in the use of psychedelic substances for the treatment of mental disorders is increasing. Processes that may afect therapeutic change are not yet fully understood. Qualitative research methods are increasingly used to examine patient accounts; however, currently, no systematic review exists that synthesizes these fndings in relation to the use of psychedelics for the treatment of mental disorders.

Objective

Exploring the Maladaptive Cognitions of Moral Injury

Moral injury and Post-Traumatic Stress Disorder (PTSD) are two prominent mental health problems that affect military personnel. Moral injury results when the individual is exposed to a situation or event that violates their moral code; however, PTSD results when there is a substantial threat of harm. Moral injury is a relatively new construct within the literature with research starting in the late 2000s. Although distorted cognitions are core components of PTSD symptomatology, there has been no research of cognitions in moral injury.

 

Absence of definitive scientific evidence that benzodiazepines could hinder the efficacy of exposure‐based interventions in adults with anxiety or posttraumatic stress disorders : A systematic review of randomized clinical trials

Background and Objectives

Exposure‐based interventions (EBIs) are the first‐line treatment for anxiety disorders and posttraumatic stress disorder. Although common, the association between EBIs and benzodiazepines is controversial. Therefore, we systematically reviewed the literature to evaluate if benzodiazepines could undermine the efficacy of EBIs in treating these disorders.

 

Methods

A new treatment approach for PTSD : High-Intensive Narrative Exposure Therapy (HI-NET)

Current international guidelines recommend Trauma-Focused Therapies (TFT) to treat Post-Traumatic Stress Disorder (PTSD). However, non-response and dropout rates have shown to be substantial. TFT, delivered in a highly intensive dose may lead to a more efficacious symptom reduction and lower dropout rates. This article describes an inpatient treatment program with Narrative Exposure Therapy (NET), called High-Intensive NET (HI-NET).

 

Efficacy of immersive PTSD treatments : A systematic review of virtual and augmented reality exposure therapy and a meta-analysis of virtual reality exposure therapy

Background: Virtual reality exposure therapy (VRET) and augmented reality exposure therapy (ARET) are digitally assisted psychotherapies that potentially enhance posttraumatic stress disorder (PTSD) treatment by increasing a patient’s sense of presence during exposure therapy. This study aimed to systematically review current evidence regarding the efficacy of VRET and ARET as PTSD treatment.

 

Treatment gap in bereavement care : (Online) bereavement support needs and use after traumatic loss

People bereaved through road traffic accidents (RTAs) are at risk for severe and disabling grief (i.e., pathological grief). Knowledge about needs and use of bereavement care, including psychotherapy, pharmacotherapy, and support groups is limited. This study charted (correlates of) the needs and use of bereavement care in RTA bereaved people. Furthermore, while online grief treatment seems effective, it is unknown whether it is perceived as acceptable. Accordingly, we examined the acceptability of online treatment.

Cognitive Therapy and EMDR for Reducing Psychopathology in Bereaved People After the MH17 Plane Crash : Findings From a Randomized Controlled Trial

Experiencing a sudden/violent loss of a significant other is a risk factor for developing persistent complex bereavement disorder (PCBD), depression, and/or posttraumatic stress disorder (PTSD). Cognitive therapy (CT) combined with eye movement desensitization and reprocessing (EMDR) might be an effective treatment for bereaved people with PCBD, depression, and/or PTSD symptoms after sudden/violent loss. We tested the effects of CT + EMDR versus waitlist controls in disaster-bereaved people.

Psychological treatments for post-traumatic stress disorder in adults : a network meta-analysis

Background
Post-traumatic stress disorder (PTSD) is a potentially chronic and disabling disorder affecting a significant minority of people exposed to trauma. Various psychological treatments have been shown to be effective, but their relative effects are not well established.

Methods

We undertook a systematic review and network meta-analyses of psychological interventions for adults with PTSD. Outcomes included PTSD symptom change scores post-treatment and at 1–4-month follow-up, and remission post-treatment.

Treating patients with severe mental illness with narrative exposure therapy for comorbid post-traumatic stress disorder

Background
Interpersonal trauma and post-traumatic stress disorder (PTSD) in patients with severe mental illness (SMI) negatively affect illness course. Narrative exposure therapy (NET) is effective in vulnerable patient groups, but its efficacy and applicability has not been studied in out-patients with SMI.

Aims
We aimed to evaluate the efficacy and applicability of NET in SMI on changes in PTSD, dissociation, SMI symptoms, care needs, quality of life, global functioning and care consumption. 

 

The impact of brief intensive trauma-focused treatment for PTSD on symptoms of borderline personality disorder

Background: It is generally recommended to exercise caution in applying trauma-focused treatment to individuals with posttraumatic stress disorder (PTSD) and comorbid borderline personality disorder (BPD).

 

Objective: To investigate the effects of a brief, intensive, direct trauma-focused treatment programme for individuals with PTSD on BPD symptom severity.

 

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