Impact of comorbid personality disorders on psychotherapy for post-traumatic stress disorder : systematic review and meta-analysis

Objective: This constitutes the first meta-analysis investigating whether patients with and without comorbid personality disorders can equally benefit from psychotherapy for PTSD.

 

Method: A systematic literature search was conducted in PubMed, EMBASE, PsychINFO and Cochrane databases from inception through 31 January 2020, to identify clinical trials examining psychotherapies for PTSD in PTSD patients with and without comorbid personality disorders (PROSPERO reference CRD42020156472).

 

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Associations between oxytocin and vasopressin concentrations, traumatic event exposure and posttraumatic stress disorder symptoms : group comparisons, correlations, and courses during an internet-based cognitive-behavioural treatment

Background: Posttraumatic stress disorder (PTSD) is characterized by impairments in extinction learning and social behaviour, which are targeted by trauma-focused cognitive behavioural treatment (TF-CBT). The biological underpinnings of TF-CBT can be better understood by adding biomarkers to the clinical evaluation of interventions. Due to their involvement in social functioning and fear processing, oxytocin and arginine vasopressin might be informative biomarkers for TF-CBT, but to date, this has never been tested.

 

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Effectiveness of animal-assisted interventions for children and adults with post-traumatic stress disorder symptoms : a systematic review and meta-analysis

Background: Animal-assisted interventions (AAI) are increasingly applied for people with post-traumatic stress disorder (PTSD) symptoms albeit its effectiveness is unclear.

 

Objectives: To examine the effectiveness of AAI for treating PTSD symptoms.

 

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A brief cognitive-behavioural treatment approach for PTSD and Dissociative Identity Disorder, a case report

Background and objectives

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Psychologic Treatment of Depression Compared With Pharmacotherapy and Combined Treatment in Primary Care : A Network Meta-Analysis

PURPOSE:  Most patients with depression are treated by general practitioners, and most of those patients prefer psychotherapy over pharmacotherapy. No network meta-analyses have examined the effects of psychotherapy compared with pharmacotherapy, combined treatment, care as usual, and other control conditions among patients in primary care.

 

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Brief Eclectic Psychotherapy for Moral Trauma (BEP-MT) : treatment protocol description and a case study

ABSTRACT

Background: Traumatic events can be related to severe transgressions or violations of moral boundaries. Moral injury (MI) has been described as ‘the lasting psychological, biological, spiritual, behavioral and social impact of perpetrating, failing to prevent, or bearing witness to acts that transgress deeply held moral beliefs and expectations.’ These events can provoke emotions such as remorse, guilt and shame, and affects someone’s self-image and identity.

 

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Does complex PTSD predict or moderate treatment outcomes of three variants of exposure therapy?

Background

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MDMA-assisted therapy for severe PTSD : a randomized, double-blind, placebo-controlled phase 3 study

Post-traumatic stress disorder (PTSD) presents a major public health problem for which currently available treatments are modestly effective. We report the findings of a randomized, double-blind, placebo-controlled, multi-site phase 3 clinical trial (NCT03537014) to test the efficacy and safety of 3,4-methylenedioxymethamphetamine (MDMA)-assisted therapy for the treatment of patients with severe PTSD, including those with common comorbidities such as dissociation, depression, a history of alcohol and substance use disorders, and childhood trauma.

 

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Rich false memories of autobiographical events can be reversed

False memories of autobiographical events can create enormous problems in forensic settings (e.g., false accusations). While multiple studies succeeded in inducing false memories in interview settings, we present research trying to reverse this effect (and thereby reduce the potential damage) by means of two ecologically valid strategies. We first successfully implanted false memories for two plausible autobiographical events (suggested by the students’ parents, alongside two true events).

 

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Sleep Quality Improvements After MDMA-Assisted Psychotherapy for the Treatment of Posttraumatic Stress Disorder

Sleep disturbances (SDs) are among the most distressing and commonly reported symptoms in posttraumatic stress disorder (PTSD). Despite increased attention on sleep in clinical PTSD research, SDs remain difficult to treat. In Phase 2 trials, 3,4-methylenedioxymethamphetamine (MDMA)–assisted psychotherapy has been shown to greatly improve PTSD symptoms. We hypothesized that MDMA-assisted psychotherapy would improve self-reported sleep quality (SQ) in individuals with PTSD and be associated with declining PTSD symptoms.

 

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