International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestryspecific genetic risk loci

The risk of posttraumatic stress disorder (PTSD) following trauma is heritable, but robust common variants have yet to be identified. In a multi-ethnic cohort including over 30,000 PTSD cases and 170,000 controls we conduct a genome-wide association study of PTSD. We demonstrate SNP-based heritability estimates of 5–20%, varying by sex. Three genome-wide significant loci are identified, 2 in European and 1 in African-ancestry analyses. Analyses stratified by sex implicate 3 additional loci in men.

Expert medico-legal reports: The relationship between levels of consistency and judicial outcomes in asylum seekers in the Netherlands

Introduction: If asylum applicants need to prove that they have been persecuted in their home country, expert judgment of the psychological and physical consequences of torture may support the judicial process. Expert medico-legal reports can be used to assess whether the medical complaints of the asylum seeker are consistent with their asylum account. It is unclear which factors influence medical expert judgement about the consistency between an asylum seeker’s symptoms and story, and to what extent expert medico-legal reports are associated with judicial outcomes.

Intergenerational consequences of the Holocaust on offspring mental health : a systematic review of associated factors and mechanisms

Exposure to war and violence has major consequences for society at large, detrimental impact on people’s individual lives, and may also have intergenerational consequences. To gain more insight into these intergenerational consequences, research addressing the impact of the Holocaust on offspring is an important source of information. The aim of the current study was to systematically review the mechanisms of intergenerational consequences by summarizing characteristics in Holocaust survivors and their offspring suggested to impact the offspring’s mental health.

Adolescent Life Perspectives After War : Evaluation and Adaptation of the Future Expectation Scale in Uganda

The formulation of life perspectives is one of the developmental tasks of adolescence. Expectations regarding one’s own future are shaped by cultural and contextual factors. However, there is little cross-cultural research that includes countries affected by war and turmoil. A Ugandan version of the Future Expectations Scale for Adolescents (FESA) was developed and evaluated with a sample of 279 Ugandan adolescents with low socioeconomic status living in rural communities affected by the Ugandan civil war (1986–2006).

Conducting research in clinical practice : Challenges in the assessment and treatment of childhood internalizing disorders

Dissertation: Radboud Universiteit Nijmegen

Vanuit de Academische Werkplaats Inside-Out onderzocht Marleen van Doorn de diagnostiek en behandeling van kinderen met angst of depressieve klachten in de klinische praktijk. Bij het stellen van een diagnose is het essentieel dat therapeuten niet alleen de visie van ouders op zulke klachten meewegen, maar ook die van het kind zelf, is een belangrijke conclusie uit het promotieonderzoek.

Onopgemerkte stoornissen 

Complex Posttraumatic Stress Disorder in Patients Exposed to Emotional Neglect and Traumatic Events : Latent Class Analysis

The inclusion of a complex posttraumatic stress disorder (CPTSD) diagnosis in the 11th revision of the International Classification of Diseases reflects growing evidence that a subgroup of individuals with PTSD also suffer from disturbances in emotion regulation, interpersonal skills, and self-concept, which together are termed “disturbances in self-organization” (DSO). Although CPTSD is assumed to result from exposure to complex traumatic events, emotional neglect may be an important contributor.

Creative arts therapy for traumatized children in South Africa : an evaluation study

 

Aim

To evaluate the feasibility and effect of a 10-session creative arts in psychotherapy group programme on posttraumatic stress symptoms, behavioural problems, and posttraumatic growth, in children who experienced a traumatic event.

 

Design

A multicentre non-randomized controlled trial with a treatment and a control condition conducted in South Africa (4 sites).

 

Methods

Stop the War on Children : Protecting Children in 21st Century Conflict

The nature of conflict has changed, putting children in the frontline in new and terrible ways. Wars are lasting longer. They are more likely to be fought in urban areas amongst civilian populations leading to deaths and life-changing injuries, and laying waste to the infrastructure needed to guarantee access to food and water. Attacks on schools and hospitals are up. The denial of humanitarian aid is used as yet another weapon of war. The international rules and basic standards of conduct that exist to protect civilians in conflict are being flouted with impunity.

 

Empowering young people who experienced domestic violence and abuse : The development of a group therapy intervention

This article describes the development of a group-based therapeutic intervention for young people (YP) who have lived with domestic violence and abuse. The intervention was informed by interviews with 107 YP, focused on their experiences of coping, resilience and agency. The intervention draws on resources from systemic, creative and narrative approaches to group work, and aims to facilitate YP’s expression of distress in a way that recognizes that it is embodied, contextual and relational.

Mental and sexual health outcomes following sexual assault in adolescents : a prospective cohort study

Background Young  people  are  disproportionately  affected  by  sexual  assault,  yet  longitudinal  data  are  sparse.  This  paper examines the characteristics of adolescents presenting to sexual assault services and mental and sexual health outcomes after an assault.

 

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