Objective: Although highly intensive trauma treatment programs show promising results in the treatment of patients with posttraumatic stress disorder (PTSD), it remains uncertain if patients with complex forms of PTSD can benefit equally from these intensive programs. To investigate whether patients with the dissociative subtype of PTSD (PTSD + DS) and patients with probable complex PTSD (CPTSD) draw equal benefits from a highly intensive trauma treatment program as patients with PTSD.

This thesis describes the studies conducted into the development and evaluation of the Dutch SAFE eHealth intervention for women who experience(d) intimate partner violence and abuse (IPVA). IPVA is a type of domestic violence and abuse (DVA) that occurs frequently in society but that is often accompanied by stigma, complicating the help seeking process. With the internet being able to offer anonymity and easy, low threshold accessibility, an online platform could be a suitable means of reaching women who experience IPVA and support them, for example in help-seeking.

The Russian invasion of Ukraine on February 24, 2022, has had devastating effects on the Ukrainian population and the global economy, environment, and political order. However, little is known about the psychological states surrounding the outbreak of war, particularly the mental well-being of individuals outside Ukraine.

MDMA (±3,4-methylenedioxymethamphetamine)-assisted therapy (MDMA-AT) was shown in previous clinical trials to have promising efficacy and safety for alleviating treatment-resistant posttraumatic stress disorder (PTSD). However, due to low ethnoracial diversity, the question remains as to whether ethnoracial minority participants would benefit similarly.