Background: Stressful events increase the risk for treatment-resistant depression (TRD), and trauma-focused psychotherapy can be useful for TRD patients exposed to early life stress (ELS). Epigenetic processes are known to be related to depression and ELS, but there is no evidence of the effects of trauma-focused psychotherapy on methylation alterations.

Objective: We performed the first epigenome-wide association study to investigate methylation changes related to trauma-focused psychotherapies effects in TRD patients.

In het Nauw is een podcastserie over Nederlandse psychiatrische instellingen tijdens de Tweede Wereldoorlog. Jodenvervolging, oorlogsgeweld, ontbering en honger: Dit trof duizenden Nederlanders die in psychiatrische instellingen leefden - en daardoor extra kwetsbaar waren. In vier afleveringen vertelt In het nauw deze onbekende geschiedenis en laat het leven van dichtbij in psychiatrische instellingen zien.

Nederland kent naar schatting twee miljoen mensen met een achtergrond in voormalig Nederlands-Indië, het huidige Indonesië. Om goede aansluiting te vinden en nog betere zorg te verlenen is het belangrijk kennis te hebben van de geschiedenis, cultuur en ervaringen van deze gemeenschap. Want wat er vroeger is gebeurd, kan nog altijd grote impact hebben. In 10 korte video’s laten we zien waar jij als zorgverlener mee te maken kunt krijgen en hoe de echo’s uit Nederlands-Indië nog altijd doorklinken.

Background:

Background: Sexual victimization is a serious public health problem, with a range of negative impacts on mental and physical health. Responses that individuals get to disclosure of sexual victimization play an important role in recovery. With the increased use of social media, more survivors are talking about their experiences of sexual victimization online. Research is needed to document the correlates of online disclosure of sexual victimization.

Background: Resilience is a modulating factor in the development of PTSD and CPTSD after exposure to traumatic events. However, the relationship between resilience and ICD-11 CPTSD is not adequately understood in survivors of intimate partner violence (IPV).

Objective: The aim of this study is to determine whether resilience has a mediating role in the relationship between severity of violence and severity of CPTSD symptoms.

Background: Young adult sexual minority women (SMW) are at elevated risk for sexual assault (SA), posttraumatic stress disorder (PTSD), and inadequate social support. While SA and PTSD can lead to reductions in social support from close significant others, the impact of SA and PTSD on SMWs’ social support has not previously been assessed.

Introduction: Healthcare workers (HCWs) often experience morally challenging situations in their workplaces that may contribute to job turnover and compromised well-being. This study aimed to characterize the nature and frequency of moral stressors experienced by HCWs during the COVID-19 pandemic, examine their influence on psychosocial-spiritual factors, and capture the impact of such factors and related moral stressors on HCWs’ self-reported job attrition intentions.

Background: Trauma-related guilt and shame are crucial for the development and maintenance of PTSD (posttraumatic stress disorder). We developed an intervention combining cognitive techniques with loving-kindness meditations (C-METTA) that specifically target these emotions. C-METTA is an intervention of six weekly individual treatment sessions followed by a four-week practice phase.

Objective: This study examined C-METTA in a proof-of-concept study within a randomized wait-list controlled trial.

Background: Refugees often suffer from trauma-related psychopathology, specifically posttraumatic stress disorder (PTSD). Negative world assumptions are strongly correlated with the development, course, and severity of PTSD.

Objective: This study aimed to investigate whether there are distinct profiles of PTSD and negative world assumptions (NWA) and examine whether trauma load, torture, and gender differentially predict such symptom profiles.