Psychiatrist, psychoanalyst, and neurologist William Guglielmo Niederland (1904–1993) received widespread acclaim for his research on Holocaust survivors, yet his other psychoanalytic work has yet to achieve comparable recognition. In this article, I will examine the affinities between Niederland’s study of the Holocaust survivors and other major works in his canon to demonstrate the cohesive nature of his worldview, philosophy, and psychoanalytic trajectory while also illuminating Niederland’s portrait of the human being. This work is divided into two sections.