Pharmacotherapy in the aftermath of trauma, opportunities in the 'golden hours'

Several lines of research have demonstrated that memories for fearful events become transiently labile upon re-exposure. Activation of molecular mechanisms is required in order to maintain retrieved information. This process is called reconsolidation. Targeting reconsolidation - as in exposure-based psychotherapy - offers therefore a potentially interesting tool to manipulate fear memories, and subsequently to treat disorders such as post-traumatic stress disorder (PTSD).

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Partner accommodation in posttraumatic stress disorder: Initial testing of the Significant Others' Responses to Trauma Scale (SORTS)

Posttraumatic stress disorder (PTSD) is associated with myriad relationship problems and psychological distress in partners of individuals with PTSD. This study sought to develop a self-report measure of partner accommodation to PTSD (i.e., ways in which partners alter their behavior in response to patient PTSD symptoms), the Significant Others' Responses to Trauma Scale (SORTS), and to investigate its reliability and construct validity in 46 treatment-seeking couples. The SORTS demonstrated strong internal consistency and associations with individual and relationship distress.

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Lessons learned from Dutch deployed surgeons and anesthesiologists to Afghanistan: 2006-2010

INTRODUCTION: Care for battle casualties demands special skills from surgeons and anesthesiologists. The experiences of Dutch military surgeons and anesthesiologists that deployed to South Afghanistan provided an opportunity to evaluate predeployment training and preparation of military medical specialistsMETHOD: A survey was conducted among all surgeons and anesthesiologists (n = 40) that deployed to South Afghanistan between February 2006 and November 2010.

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In memoriam: Edward J. Frischholz, PhD, January 14, 1956-May 10, 2014

We sadly lost our friend and colleague Edward J. (“Fast Eddie”) Frischholz, PhD, at the young age of 58. He died of heart failure, a complication of septic shock. He was a passionate advocate for the field of hypnosis, a tough monitor of its quality, a fine clinician, and an excellent researcher/statistician.

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Indications of an altered one-carbon metabolism in chronic posttraumatic stress disorder

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Iraq and Afghanistan War Veterans with Reintegration Problems: Differences by Veterans Affairs Healthcare User Status

We studied 1,292 Iraq and Afghanistan War veterans who participated in a clinical trial of expressive writing to estimate the prevalence of perceived reintegration difficulty and compare Veterans Affairs (VA) healthcare users to nonusers in terms of demographic and clinical characteristics. About half of participants perceived reintegration difficulty. VA users and nonusers differed in age and military background. Levels of mental and physical problems were higher in VA users.

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Executive function in posttraumatic stress disorder (PTSD) and the influence of comorbid depression

BackgroundPosttraumatic stress disorder (PTSD) has been associated with neurocognitive deficits, such as impaired verbal memory and executive functioning. Less is known about executive function and the role of comorbid depression in PTSD.

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Examining the Factor Structure of the Connor-Davidson Resilience Scale (CD-RISC) in a Post-9/11 U.S. Military Veteran Sample

The present study examined the structural validity of the 25-item Connor-Davidson Resilience Scale (CD-RISC) in a large sample of U.S. veterans with military service since September 11, 2001. Participants (N = 1,981) completed the 25-item CD-RISC, a structured clinical interview and a self-report questionnaire assessing psychiatric symptoms. The study sample was randomly divided into two subsamples: an initial sample (Sample 1: n = 990) and a replication sample (Sample 2: n = 991).

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Efficacy of oxytocin administration early after psychotrauma in preventing the development of PTSD: study protocol of a randomized controlled trial

BackgroundCurrently few evidence based interventions are available for the prevention of PTSD within the first weeks after trauma. Increased risk for PTSD development is associated with dysregulated fear and stress responses prior to and shortly after trauma, as well as with a lack of perceived social support early after trauma. Oxytocin is a potent regulator of these processes. Therefore, we propose that oxytocin may be important in reducing adverse consequences of trauma.

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Effects of Cognitive–Behavioral Conjoint Therapy for PTSD on Partners' Psychological Functioning

A number of studies have documented that posttraumatic stress disorder (PTSD) symptoms in 'one' partner are negatively associated with their intimate partner's psychological functioning. The present study investigated intimate partners' mental health outcomes (i.e., depression, anxiety, and anger) in a sample of 40 partners of individuals with PTSD within a randomized waitlist controlled trial of cognitive–behavioral conjoint therapy for PTSD (Monson & Fredman, 2012).

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