Hippocampal Threat Reactivity Interacts with Physiological Arousal to Predict PTSD Symptoms

Prior studies highlighthow threat-related arousal may impair hippocampal function. Hippocampal impairments are reliably associated with post-traumatic stress disorder(PTSD); however, little research has characterized how increased threat-sensitivity may drive arousal responses to alter hippocampal reactivity, and further how these alterationsrelate to the sequelae of trauma-related symptoms.

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Defining and Assessing the Syndrome of Moral Injury : Initial Findings of the Moral Injury Outcome Scale Consortium

Potentially morally injurious events (PMIEs) entail acts of commission (e.g., cruelty, proscribed or prescribed violence) or omission (e.g., high stakes failure to protect others) and bearing witness (e.g., to grave inhumanity, to the gruesome aftermath of violence), or being the victim of others' acts of commission (e.g., high stakes trust violations) or omission (e.g., being the victim of grave individual or systemic failures to protect) that transgress deeply held beliefs and expectations about right and wrong.

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Shared sources and mechanisms of healthcare worker distress in COVID-19 : a comparative qualitative study in Canada and the UK

Background: COVID-19 has had a significant impact on the wellbeing of healthcare workers, with quantitative studies identifying increased stress, anxiety, depression, insomnia, and PTSD in a wide range of settings. Limited qualitative data so far has offered in-depth details concerning what underlies these challenges, but none provide comprehensive comparison across different healthcare systems.

 

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Factors influencing the mental health of an ethnically diverse healthcare workforce during COVID-19 : a qualitative study in the United Kingdom

Background: Healthcare workers (HCWs) have been reported to be experiencing a deterioration in their mental health due to COVID-19. In addition, ethnic minority populations in the United Kingdom are disproportionately affected by COVID-19. It is imperative that HCWs are appropriately supported and protected from mental harm during the pandemic. Our research aims to add to the evidence base by providing greater insight into the lived experience of HCWs from diverse ethnic backgrounds during the pandemic that had an impact on their mental health.

 

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Adiponectin gene polymorphisms and posttraumatic stress disorder symptoms among female rape survivors : an exploratory study

Background: Rape is a common traumatic event which may result in the development of posttraumatic stress disorder (PTSD), yet few studies have investigated risk biomarkers in sexually traumatised individuals. Adiponectin is a novel cytokine within inflammatory and cardiometabolic pathways with evidence of involvement in PTSD.

 

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Using network analysis to illuminate the intergenerational transmission of adversity

Objective: The effects of maternal exposure to adverse childhood experiences (ACEs) may be transmitted to subsequent generations through various biopsychosocial mechanisms. However, studies tend to focus on exploring one or two focal pathways with less attention paid to links between different pathways. Using a network approach, this paper explores a range of core prenatal risk factors that may link maternal ACEs to infant preterm birth (PTB) and low birthweight (LBW).

 

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Grief in women with previous miscarriage or stillbirth : a systematic review of cross-sectional and longitudinal prospective studies

Background: Women who have had miscarriages or stillbirths are known to have a high risk for enduring grief. However, the course and frequency of enduring grief in this subgroup are not fully understood.

 

Objective: Our aims were to assess the intensity of grief and its course in women with miscarriages or stillbirths and to estimate the frequency of severe grief reactions in this population. Additionally, we compared subgroups with miscarriages versus stillbirths and with single versus recurrent pregnancy loss.

 

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A comparison of methods to harmonize cortical thickness measurements across scanners and sites

Results of neuroimaging datasets aggregated from multiple sites may be biased by site-specific profiles in participants’ demographic and clinical characteristics, as well as MRI acquisition protocols and scanning platforms.

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Text mining to improve screening for trauma-related symptoms in a global sample

Previous studies showed that textual information could be used to screen respondents for posttraumatic stress disorder (PTSD). In this study, we explored the feasibility of using language features extracted from short text descriptions respondents provided of stressful events to predict trauma-related symptoms assessed using the Global Psychotrauma Screen. Texts were analyzed with both closed- and open-vocabulary methods to extract language features representing the occurrence of words, phrases, or specific topics in the description of stressful events.

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Family History of Psychiatric Disorders as a Risk Factor for Maternal Postpartum Depression : A Systematic Review and Meta-analysis

Importance  Current evidence on the association between family history of psychiatric disorders and postpartum depression is inconsistent; family studies have identified familial risk of postpartum depression, whereas systematic reviews and umbrella reviews, compiling all risk factors for postpartum depression, often have not.

 

Objective  To investigate the association between family history of psychiatric disorders and risk of developing postpartum depression within 12 months post partum.

 

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