Previous investigations of whole thalamus and thalamic nuclei volumes in post-trauma psychopathology have been sparse, limited in scope, and yielded inconsistent results. To address this, volumetric estimates of whole thalamus and thalamic nuclei were obtained from structural brain MRI scans from 2,058 participants across 20 worldwide sites in the ENIGMA PTSD working group.

The increasing scale and complexity of neuroimaging datasets aggregated from multiple study sites present substantial analytic challenges, as existing statistical analysis tools struggle to handle missing voxel-data, suffer from limited computational speed and inefficient memory allocation, and are restricted in the types of statistical designs they are able to model.

Potentially traumatic events (PTEs) are prevalent among Indonesian students. Web-based psychoeducation might increase mental health literacy and reduce barriers to healthcare access. We developed Pulihkan Luka (PL), a web-based psychoeducation programme for Indonesian undergraduate students. This pilot randomized controlled trial assessed the feasibility, acceptability, and preliminary efficacy of PL. Students (N = 130) were randomly assigned to (1) four to seven sessions of PL + Enhanced Usual Care (PL+EUC; n = 64) or (2) EUC only (n = 66).

Prolonged grief disorder (PGD) is a new diagnostic category included in global diagnostic classification systems for mental disorders. However, PGD can only be diagnosed if the severity and duration exceed socio-cultural norms. Here, we present a new supplementary module to the DSM-5 Cultural Formulation Interview: the Bereavement and Grief Cultural Formulation Interview (BG-CFI). The BG-CFI was developed to help clinicians provide a culturally informed diagnosis and guide treatment planning.