Perspectives on dying in severe and enduring eating disorders (SEEDs) : A qualitative study among Dutch mental healthcare providers

Dying of severe and enduring eating disorders (SEEDs) was studied using semi-structured interviews (n=7) and a follow-up videoconferencing focus group (n=3) with Dutch mental healthcare providers. We identified three main themes: the uncertainties of dying from SEEDs, dilemmas in defining treatment resistance and palliative care, and suicidal ideation and intent.

 

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Smaller total and subregional cerebellar volumes in posttraumatic stress disorder : a mega-analysis by the ENIGMA-PGC PTSD workgroup

Although the cerebellum contributes to higher-order cognitive and emotional functions relevant to posttraumatic stress disorder (PTSD), prior research on cerebellar volume in PTSD is scant, particularly when considering subregions that differentially map on to motor, cognitive, and affective functions.

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The role of guilt-shame proneness and locus of control in predicting moral injury among healthcare professionals

Despite the advances in studies conducted among healthcare professionals to explore the impact of the pandemic on their mental health, a large population still continues to display COVID-19 related psychological complaints. There has been recent awareness of moral injury related guilt and shame among doctors and nurses. However, the factors associated with moral injury have not received much attention, due to which the issue still persists. This study aims to explore the role of guilt-shame proneness, and locus of control in predicting moral injury among healthcare professionals.

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Holocaust survivors : Health and longevity 70 years later

Background
Holocaust survivors (HS) alive today form a unique and disappearing population, whose exposure to systematic genocide occurred over 70 years ago. Negative health outcomes were widely documented prior to age 70. We examine the hypothesis that the experience of remote trauma continues to negatively affect health, functional status, and survival between the ages of 85–95.

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Long-lasting effects of World War II trauma on PTSD symptoms and embodiment levels in a national sample of Poles

The main aim of this study was to investigate the long-lasting influences of World War II (WWII) trauma in a national sample of Poles, based on Danieli’s (1998) survivors’ post-trauma adaptational styles (fighter, numb, victim) and their link with current post-traumatic stress disorder (PTSD) symptoms and embodiment level among participants. We also sought to investigate whether the level of knowledge about WWII trauma among ancestors could moderate that association.

 

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Lifelong effects of prenatal and early postnatal stress on the hippocampus, amygdala, and psychological states of Holocaust survivors

This study focuses on hippocampal and amygdala volume, seed-based connectivity, and psychological traits of Holocaust survivors who experienced stress during prenatal and early postnatal development. We investigated people who lived in Central Europe during the Holocaust and who, as Jews, were in imminent danger. The group who experienced stress during their prenatal development and early postnatal (PreP) period (n = 11) were compared with a group who experienced Holocaust-related stress later in their lives: in late childhood, adolescence, and early adulthood (ChA) (n = 21).

 

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Impaired learning, memory, and extinction in posttraumatic stress disorder : translational meta-analysis of clinical and preclinical studies

Current evidence-based treatments for post-traumatic stress disorder (PTSD) are efficacious in only part of PTSD patients. Therefore, novel neurobiologically informed approaches are urgently needed. Clinical and translational neuroscience point to altered learning and memory processes as key in (models of) PTSD psychopathology. We extended this notion by clarifying at a meta-level (i) the role of information valence, i.e. neutral versus emotional/fearful, and (ii) comparability, as far as applicable, between clinical and preclinical phenotypes.

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Unity or Anarchy? : A Historical Search for the Psychological Consequences of Psychotrauma

The field of traumatic stress is often referred to as being in a state of controversy and lack of continuity. Throughout history, disputes repeatedly centered on defining the psychological consequences of severe adverse events and on their causes. Even to this day this is current. To understand these controversies, an extensive historical literature review is presented of how mental consequences of trauma have been described in history, of the circumstances in which this took place, and of the disputes that have influenced the conceptualization of these mental responses.

 

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Functional brain changes after alternative pharmacological interventions in posttraumatic stress disorder : A systematic review of clinical trials

Background
Posttraumatic stress disorder (PTSD) is a complex and heterogeneous mental health condition that can develop after exposure to a traumatic event. Clinical trials have used alternative pharmacological agents to treat PTSD, but their associated neural correlates remain unclear. The present systematic review aims to summarize the changes in brain function associated with the use of these alternative pharmacological agents in PTSD.

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Factors associated with mental health of young children during the COVID-19 pandemic in the Netherlands

Background
The COVID-19 pandemic and accompanying societal measures have impacted children and their families all over the world. Little is known about the factors associated with mental health outcomes in young children (i.e., 1 to 6 years old) during the pandemic. The current study aimed to examine associations with potential risk and protective factors, i.e., direct COVID-19 exposure factors as well as within-family characteristics.

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