Lessons learned from Dutch deployed surgeons and anesthesiologists to Afghanistan: 2006-2010

INTRODUCTION: Care for battle casualties demands special skills from surgeons and anesthesiologists. The experiences of Dutch military surgeons and anesthesiologists that deployed to South Afghanistan provided an opportunity to evaluate predeployment training and preparation of military medical specialistsMETHOD: A survey was conducted among all surgeons and anesthesiologists (n = 40) that deployed to South Afghanistan between February 2006 and November 2010.

Read more

Iraq and Afghanistan War Veterans with Reintegration Problems: Differences by Veterans Affairs Healthcare User Status

We studied 1,292 Iraq and Afghanistan War veterans who participated in a clinical trial of expressive writing to estimate the prevalence of perceived reintegration difficulty and compare Veterans Affairs (VA) healthcare users to nonusers in terms of demographic and clinical characteristics. About half of participants perceived reintegration difficulty. VA users and nonusers differed in age and military background. Levels of mental and physical problems were higher in VA users.

Read more

In memoriam: Edward J. Frischholz, PhD, January 14, 1956-May 10, 2014

We sadly lost our friend and colleague Edward J. (“Fast Eddie”) Frischholz, PhD, at the young age of 58. He died of heart failure, a complication of septic shock. He was a passionate advocate for the field of hypnosis, a tough monitor of its quality, a fine clinician, and an excellent researcher/statistician.

Read more

Indications of an altered one-carbon metabolism in chronic posttraumatic stress disorder

Read more

Executive function in posttraumatic stress disorder (PTSD) and the influence of comorbid depression

BackgroundPosttraumatic stress disorder (PTSD) has been associated with neurocognitive deficits, such as impaired verbal memory and executive functioning. Less is known about executive function and the role of comorbid depression in PTSD.

Read more

Examining the Factor Structure of the Connor-Davidson Resilience Scale (CD-RISC) in a Post-9/11 U.S. Military Veteran Sample

The present study examined the structural validity of the 25-item Connor-Davidson Resilience Scale (CD-RISC) in a large sample of U.S. veterans with military service since September 11, 2001. Participants (N = 1,981) completed the 25-item CD-RISC, a structured clinical interview and a self-report questionnaire assessing psychiatric symptoms. The study sample was randomly divided into two subsamples: an initial sample (Sample 1: n = 990) and a replication sample (Sample 2: n = 991).

Read more

Effects of Cognitive–Behavioral Conjoint Therapy for PTSD on Partners' Psychological Functioning

A number of studies have documented that posttraumatic stress disorder (PTSD) symptoms in 'one' partner are negatively associated with their intimate partner's psychological functioning. The present study investigated intimate partners' mental health outcomes (i.e., depression, anxiety, and anger) in a sample of 40 partners of individuals with PTSD within a randomized waitlist controlled trial of cognitive–behavioral conjoint therapy for PTSD (Monson & Fredman, 2012).

Read more

Effects of oxidative stress on fatty acid- and one-carbon-metabolism in psychiatric and cardiovascular disease comorbidity

ObjectiveCardiovascular disease (CVD) is the leading cause of death in severe psychiatric disorders (depression, schizophrenia). Here, we provide evidence of how the effects of oxidative stress on fatty acid (FA) and one-carbon (1-C) cycle metabolism, which may initially represent adaptive responses, might underlie comorbidity between CVD and psychiatric disorders.MethodWe conducted a literature search and integrated data in a narrative review.ResultsOxidative stress, mainly generated in mitochondria, is implicated in both psychiatric and cardiovascular pathophysiology.

Read more

Effects of Psychotherapy on DNA Strand Break Accumulation Originating from Traumatic Stress

Background: Previous research reveals an association between traumatic stress and an increased risk for numerous diseases, including cancer. At the molecular level, stress may increase carcinogenesis via increased DNA damage and impaired DNA repair mechanisms. We assessed DNA breakage in peripheral blood mononuclear cells from individuals with post-traumatic stress disorder (PTSD) and measured the cellular capacity to repair single-strand breaks after exposure to ionizing X-radiation. We also investigated the effect of psychotherapy on both DNA breakage and DNA repair.

Read more

Efficacy of oxytocin administration early after psychotrauma in preventing the development of PTSD: study protocol of a randomized controlled trial

BackgroundCurrently few evidence based interventions are available for the prevention of PTSD within the first weeks after trauma. Increased risk for PTSD development is associated with dysregulated fear and stress responses prior to and shortly after trauma, as well as with a lack of perceived social support early after trauma. Oxytocin is a potent regulator of these processes. Therefore, we propose that oxytocin may be important in reducing adverse consequences of trauma.

Read more

Pages