The present article offers an overview discussion of ethnocultural aspects of PTSD, with special attention to major conceptual issues, clinical considerations, and therapy practices. The historical circumstances leading to the widespread acceptance of PTSD among conventional mental health professionals, and the subsequent criticisms that emerged from scholars, humanitarian workers, and ethnocultural minorities are presented as an important background to the current controversial status of the concept, especially with regard to arguments regarding the ethnocultural determinants of PTSD.