Cost-effectiveness of massed versus spaced trauma-focused treatment as first-line treatment for post-traumatic stress disorder in adults with multiple trauma exposure : protocol for a single-blind non-inferiority randomised controlled trial

Introduction: Post-traumatic stress disorder (PTSD) is a serious disorder that burdens individuals and society. The current standard of first-line treatment for PTSD is spaced trauma-focused treatment (S-TFT), involving weekly sessions. While effective, S-TFT may take relatively long to complete, especially in patients exposed to multiple potentially traumatic events (PTEs).

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Prolonged grief disorder

Prolonged grief disorder is a mental health disorder recently included in diagnostic manuals worldwide. This Review presents published research evidence in strong support for the current conceptualisation of prolonged grief disorder:
a diagnosable mental health condition with core symptoms of yearning, preoccupation, or both, which is associated with symptoms of emotional pain, identity disturbances, loss of meaning and purpose, and functional impairment.

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Efficacy of Cognitive Behavioral Therapies With a Trauma Focus for Posttraumatic Stress Disorder : An Individual Participant Data Meta-Analysis

Objective: This individual participant data meta-analysis aimed to investigate the effectiveness of cognitive behavioral therapy with a trauma focus (CBT-TF) for posttraumatic stress disorder (PTSD). Furthermore, we examined the effect of moderators on PTSD symptom severity.

 

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Cognitive Behavior Therapy for Mental Disorders in Adults : A Unified Series of Meta-Analyses

Importance  Cognitive behavior therapy (CBT) is a first-line treatment for most mental disorders. However, no meta-analytic study has yet integrated the results of randomized clinical trials on CBT across different disorders, using uniform methodologies and providing a complete overview of the field.

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A theoretical perspective on the role of sleep in borderline personality disorder : From causative factor to treatment target

Sleep plays a crucial role in emotion regulation. Disturbed sleep is therefore increasingly seen as a potential causal factor for the development and maintenance of affective psychiatric disorders. This may hold especially for borderline personality disorder (BPD), a core emotion dysregulation disorder. Although BPD is strongly associated with sleep disturbances such as insomnia, nightmares and circadian dysrhythmia, research into the role of sleep in BPD remains sparse.

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Exploring the potential of psychedelic-assisted psychotherapy for moral injury : A scoping review

This scoping review addresses the need to comprehensively explore the potential of psychedelic-assisted psychotherapy (PAP) to facilitate recovery from moral injury. Moral injury (MI), characterized by profound psychological distress arising from morally challenging experiences, has garnered increased attention as a complex mental health concern with significant functional sequelae, especially in the context of post-traumatic stress disorder (PTSD).

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Randomized Trial of a Generative AI Chatbot for Mental Health Treatment

Background

Generative artificial intelligence (Gen-AI) chatbots hold promise for building highly personalized, effective mental health treatments at scale, while also addressing user engagement and retention issues common among digital therapeutics. We present a randomized controlled trial (RCT) testing an expert–fine-tuned Gen-AI–powered chatbot, Therabot, for mental health treatment.

Methods

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Efficacy of psychological interventions for complex post-traumatic stress disorder in adults exposed to complex traumas : A meta-analysis of randomized controlled trials

Introduction: Effective treatments for post-traumatic stress disorder (PTSD) have been established, but their applicability in complex post-traumatic stress disorder (CPTSD) is largely unknown.
 

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Access to treatment protocols and manuals for evidence-based psychological interventions for severe mental disorders : a survey of randomised trials included in network meta-analyses

Background Evidence-based psychological interventions for mental disorders are described in treatment protocols and manuals, which detail treatment components and conditions of application. Systematic evaluations of the accessibility of treatment protocols and manuals across multiple mental disorders are absent.

 

Objective We assessed whether treatment protocols or manuals for psychological interventions for severe mental disorders are accessible and publicly available.

 

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Mind–body intervention for post-traumatic stress disorder in adolescents : a systematic review and network meta-analysis

Background
Post-traumatic stress disorder (PTSD) is a potentially disabling condition that can lead to long-term impairments, with a significant proportion of adolescents being affected by trauma. Studies have suggested that trauma-focused cognitive behavioral therapy (TF-CBT) is an effective treatment for PTSD in adolescents, however, little is known about the relative advantages of different mind–body interventions. The network meta-analysis aims to evaluate and compare the efficacy of various mind–body interventions in alleviating PTSD symptoms in adolescents.

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